"Saturday Night Live", which ironically Deb was popular around the same time the show was improving after the mid '80's slump with Phil Hartman, Dana Carvey, Mike Myers, etc in the cast.
Wouldn't mind if Deb does a mythical action/adventure flick. Wouldn't be far fetched considering she did movies for SyFy.
Especially as a villian, which I'm very sure she could be "over the top" or hammy.

Since Deb is a fan of "Glee", I'm sure she'd probably appear in an instant if the producers asked her.